Erythema multiforme - Eritema Multiforme
☆ Nos resultados de Stiftung Warentest de Alemaña de 2022, a satisfacción dos consumidores con ModelDerm foi só lixeiramente inferior á das consultas de telemedicina pagas.
Erythema multiforme minor ― Teña en conta que os centros das lesións poden branquear.
A urticaria tamén se pode considerar como un diagnóstico diferencial.
References
Erythema multiforme (EM) é unha afección na que aparecen manchas distintivas semellantes á diana tanto na pel como nas mucosas debido ás reaccións inmunes. Aínda que moitas veces se desencadean por infeccións virais, especialmente o virus do herpes simple (HSV) , ou por certos medicamentos, a causa segue sendo descoñecida en moitos casos. O tratamento da EM aguda céntrase en aliviar os síntomas usando cremas que conteñan esteroides ou antihistamínicos. A xestión da EM recorrente é máis eficaz cando se adapta a cada paciente. Os enfoques iniciais inclúen tratamentos tanto orais como tópicos. Estes inclúen corticosteroides e medicamentos antivirais. Os tratamentos tópicos consisten en cremas de esteroides fortes e solucións para as membranas mucosas afectadas. Para os pacientes que non responden aos antivirais, as opcións de segunda liña inclúen medicamentos inmunosupresores, antibióticos, antihelmínticos e antipalúdicos.
Erythema multiforme (EM) is an immune-mediated condition that classically presents with discrete targetoid lesions and can involve both mucosal and cutaneous sites. While EM is typically preceded by viral infections, most notably herpes simplex virus (HSV), and certain medications, a large portion of cases are due to an unidentifiable cause. Treatment for acute EM is focused on relieving symptoms with topical steroids or antihistamines. Treatment for recurrent EM is most successful when tailored to individual patients. First line treatment for recurrent EM includes both systemic and topical therapies. Systemic therapies include corticosteroid therapy and antiviral prophylaxis. Topical therapies include high-potency corticosteroids, and antiseptic or anesthetic solutions for mucosal involvement. Second-line therapies for patients who do not respond to antiviral medications include immunosuppressive agents, antibiotics, anthelmintics, and antimalarials
Erythema multiforme (EM) is an immune-mediated condition that classically presents with discrete targetoid lesions and can involve both mucosal and cutaneous sites. While EM is typically preceded by viral infections, most notably herpes simplex virus (HSV), and certain medications, a large portion of cases are due to an unidentifiable cause. Treatment for acute EM is focused on relieving symptoms with topical steroids or antihistamines. Treatment for recurrent EM is most successful when tailored to individual patients. First line treatment for recurrent EM includes both systemic and topical therapies. Systemic therapies include corticosteroid therapy and antiviral prophylaxis. Topical therapies include high-potency corticosteroids, and antiseptic or anesthetic solutions for mucosal involvement. Second-line therapies for patients who do not respond to antiviral medications include immunosuppressive agents, antibiotics, anthelmintics, and antimalarials
En moitos casos, o erythema multiforme leve desaparece por si só dentro de 2 a 4 semanas. A síndrome de Stevens-Johnson, unha condición grave que afecta as membranas mucosas, pode durar ata 6 semanas. Os esteroides normalmente non se recomendan para casos leves. Non se sabe se os esteroides deben usarse para o eritema multiforme grave xa que non hai resultados claros de estudos aleatorios que indiquen cales nenos se beneficiarían deste tratamento.
In most cases, mild erythema multiforme is self-limited and resolves in 2 to 4 weeks. Stevens-Johnson syndrome is a serious disease that involves the mucous membranes and lasts up to 6 weeks. There is no indication for using steroids for the mild form. Use of steroids for erythema multiforme major is debatable because no randomized studies clearly indicate which children will benefit from this treatment.
In most cases, mild erythema multiforme is self-limited and resolves in 2 to 4 weeks. Stevens-Johnson syndrome is a serious disease that involves the mucous membranes and lasts up to 6 weeks. There is no indication for using steroids for the mild form. Use of steroids for erythema multiforme major is debatable because no randomized studies clearly indicate which children will benefit from this treatment.
Presentamos un caso de erythema multiforme (EM) oral causado por TMP/SMX , que mostra úlceras bucais e labiais típicas sen lesións cutáneas. Isto subliña a necesidade de diferencialo doutros trastornos ulcerativos bucais. O paciente recibiu tratamento sintomático e comprimidos de prednisolona, o que provocou unha mellora despois de interromper a terapia con TMP/SMX.
We report a case of oral erythema multiforme (EM) secondary to TMP/SMX that presented with oral and lip ulcerations typical of EM without any skin lesions and highlights the importance of distinguishing them from other ulcerative disorders involving oral cavity. The patient was treated symptomatically and given tablet prednisolone. The condition improved with stoppage of TMP/SMX therapy.
We report a case of oral erythema multiforme (EM) secondary to TMP/SMX that presented with oral and lip ulcerations typical of EM without any skin lesions and highlights the importance of distinguishing them from other ulcerative disorders involving oral cavity. The patient was treated symptomatically and given tablet prednisolone. The condition improved with stoppage of TMP/SMX therapy.
Erythema multiforme é unha reacción que implica a pel e ás veces a mucosa, desencadeada polo sistema inmunitario. Normalmente, maniféstase como lesións tipo diana, que poden aparecer illadas, repetirse ou persistir. Estas lesións adoitan afectar simétricamente ás extremidades, especialmente ás súas superficies externas. As principais causas inclúen infeccións como o virus do herpes simple e Mycoplasma pneumoniae, así como certos medicamentos, inmunizacións e enfermidades autoinmunes. Distinguir erythema multiforme da urticaria depende da duración das lesións; As lesións erythema multiforme permanecen fixas durante polo menos sete días, mentres que as lesións urticariais adoitan desaparecer nun día. Aínda que é similar, é fundamental diferenciar erythema multiforme da síndrome de Stevens-Johnson máis grave, que normalmente presenta máculas eritematosas ou purpúricas xeneralizadas con burbullas. Xestionar erythema multiforme implica un alivio sintomático con esteroides tópicos ou antihistamínicos e abordar a causa subxacente. Para os casos recorrentes asociados ao virus do herpes simple, recoméndase a terapia antiviral profiláctica. A afectación grave da mucosa pode requirir hospitalización por fluídos intravenosos e substitución de electrólitos.
Erythema multiforme is a reaction involving the skin and sometimes the mucosa, triggered by the immune system. Typically, it manifests as target-like lesions, which may appear isolated, recur, or persist. These lesions usually symmetrically affect the extremities, particularly their outer surfaces. The main causes include infections like herpes simplex virus and Mycoplasma pneumoniae, as well as certain medications, immunizations, and autoimmune diseases. Distinguishing erythema multiforme from urticaria relies on the duration of lesions; erythema multiforme lesions remain fixed for at least seven days, while urticarial lesions often vanish within a day. Although similar, it's crucial to differentiate erythema multiforme from the more severe Stevens-Johnson syndrome, which typically presents widespread erythematous or purpuric macules with blisters. Managing erythema multiforme involves symptomatic relief with topical steroids or antihistamines and addressing the underlying cause. For recurrent cases associated with herpes simplex virus, prophylactic antiviral therapy is recommended. Severe mucosal involvement may necessitate hospitalization for intravenous fluids and electrolyte replacement.
Erythema multiforme is a reaction involving the skin and sometimes the mucosa, triggered by the immune system. Typically, it manifests as target-like lesions, which may appear isolated, recur, or persist. These lesions usually symmetrically affect the extremities, particularly their outer surfaces. The main causes include infections like herpes simplex virus and Mycoplasma pneumoniae, as well as certain medications, immunizations, and autoimmune diseases. Distinguishing erythema multiforme from urticaria relies on the duration of lesions; erythema multiforme lesions remain fixed for at least seven days, while urticarial lesions often vanish within a day. Although similar, it's crucial to differentiate erythema multiforme from the more severe Stevens-Johnson syndrome, which typically presents widespread erythematous or purpuric macules with blisters. Managing erythema multiforme involves symptomatic relief with topical steroids or antihistamines and addressing the underlying cause. For recurrent cases associated with herpes simplex virus, prophylactic antiviral therapy is recommended. Severe mucosal involvement may necessitate hospitalization for intravenous fluids and electrolyte replacement.
A condición varía desde unha erupción cutánea leve e autolimitada ata unha forma grave que ameaza a vida coñecida como eritema multiforme maior que tamén implica membranas mucosas. A invasión da membrana mucosa ou a presenza de bullas son signos importantes de gravidade.
- Erythema multiforme minor: dianas típicas ou pápulas edematosas elevadas distribuídas acralmente
A forma leve adoita presentar coceira leve (pero a coceira pode ser moi severa), manchas rosa-vermellas, dispostas simétricamente e que comezan nas extremidades. A resolución da erupción cutánea en 7-10 días é a norma nesta forma da enfermidade.
- Erythema multiforme major: dianas típicas ou pápulas edematosas elevadas distribuídas acralmente con afectación dunha ou varias mucosas. O desprendemento epidérmico implica menos do 10% da superficie corporal total.
○ Tratamento - Medicamentos OTC
Se vai acompañado de febre (aumento da temperatura corporal), recoméndase visitar o hospital canto antes.
As drogas sospeitosas deben ser interrompidas. (por exemplo, antibióticos, antiinflamatorios non esteroides)
Antihistamínicos orais como cetirizina e loratadina para a comezón.
#Cetirizine [Zytec]
#LevoCetirizine [Xyzal]
#Loratadine [Claritin]